Edwards Air Force Base

Base Background

Location Edwards Air Force Base, California, United States
Years of Operation 1940-Present

Edwards Air Force Base is located in Kern County, CA, about 22 miles from Lancaster and 15 miles from Rosamond. It first opened in the 1930’s as a bombing range. The base then expanded as a flight center during World War II, running its first aircraft test in 1942. The base has since continued flight testing operations.

The 95th Air Base Wing currently operates the base, and there are 10,000 military personnel and family members living there. The base houses the 412th Test Wing, NASA’s Dryden Flight Research Center, and the United State Air Force Test Pilot School.

Known Toxins

The following chart outlines the medical conditions associated with toxic exposure at this base, classified by the strength of evidence required (strong, good or limited).* Please keep in mind that it is not a complete list.

Toxin Potential Effects
Strong Good Limited
Aluminium Potential Effects Lung cancer, Bronchitis ­ chronic Spasticity/Myoclonus, Seizures, Pneumonitis hypersensitivity, Dementia, Decreased Coordination/ Dysequilibrium, Asthma ­ allergic Sarcoidosis, Pulmonary fibrosis, Pulmonary edema, Porphyria ­ toxic, Parkinson's disease/Movement disorders, Coronary artery disease, peripheral vascular disease, atherosclerosis, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Alzheimer's, ALS (Lou Gehrig's disease), Abnormal sperm (morphology, motility, and sperm count)
Antimony Potential Effects Bronchitis ­ chronic COPD ­chronic obstructive pulmonary disease, Arrhythmias Pulmonary edema, Nasal septal perforation, Menstrual disorders, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Bladder cancer, Anemia ­ hemolytic, Acute hepatocellular injury (Hepatitis)
Arsenic Potential Effects Peripheral neuropathy, Hyperkeratosis/Hyperpigmentation, Diabetes ­ Type II, Coronary artery disease, peripheral vascular disease, atherosclerosis Steatosis (fatty liver), Skeletal malformations, Renal (kidney) cancer, Raynaud's phenomenon, Pneumonitis hypersensitivity, Neural tube defects/CNS malformations, Nasal septal perforation, Myocardial ischemia, Low birth weight/Small for Gestational Age, Hypertension, Hepatoportal Sclerosis, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Congenital malformations ­ general, Cirrhosis, Cardiomyopathy, Bladder cancer, Arrhythmias, Anemia ­ hemolytic, Alopecia, Adult­-Onset Leukemias Neurosthenia (Organic affective syndrome), Myelodysplastic syndrome, Metal fume fever, Immune suppression, Hepatocellular cancer (Liver cancer), Genito­urinary malformations (includes cryptorchidism, hypospadias), Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Acute tubular necrosis
Benzene Potential Effects Myelodysplastic syndrome, Multiple myeloma, Aplastic anemia Scleroderma, Renal (kidney) cancer, Pre­term delivery, Menstrual disorders, Lymphoma non ­Hodgkin's, Autoimmune antibodies, positive ANA, Arrhythmias Peripheral neuropathy, Neural tube defects/CNS malformations, Nasopharyngeal/Sino­Nasal cancer, Lung cancer, Immune suppression, Hepatocellular cancer (Liver cancer), Cardiac congenital malformations, Breast cancer, Brain cancer ­adult, Asthma ­irritant
Benzo A Pyrene Potential Effects Lung cancer Skin cancer (non­melanoma), Lung cancer, Immune suppression, Bladder cancer Reduced Fertility Male (infertility and subfertility)
Cadmium Potential Effects Renal stones, Osteoporosis, Itai­itai disease, Chronic renal disease, Acute tubular necrosis Reduced Fertility Male (infertility and subfertility), Prostate cancer, Pneumonia, Nephrotic syndrome, COPD ­chronic obstructive pulmonary disease, Cardiomyopathy, Anemia ­ hemolytic Testicular cancer, Soft tissue sarcoma, Renal (kidney) cancer, Pulmonary fibrosis, Pulmonary edema, Peripheral neuropathy, Pancreatic cancer, Oral clefts (cleft lip and palate), Neural tube defects/CNS malformations, Metal fume fever, Menstrual disorders, Immune suppression, Hypoactivity, Hypertension, Genito­urinary malformations (includes cryptorchidism, hypospadias), Decreased I.Q../Mental retardation, Congenital malformation Cranio­ Facial, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Brain cancer ­adult, Autoimmune antibodies, positive ANA, Arrhythmias, ADD/ADHD, hyperactivity, Abnormal sperm (morphology, motility, and sperm count)
Carbon tetrachloride Potential Effects Steatosis (fatty liver), Cirrhosis, Acute tubular necrosis, Acute hepatocellular injury (Hepatitis) Scleroderma, Porphyria ­ toxic, Lymphoma non ­Hodgkin's, Childhood Leukemias, Autoimmune antibodies, positive ANA, Arrhythmias, Aplastic anemia, Adult­-Onset Leukemias Renal (kidney) cancer, Pancreatitis, Pancreatic cancer, Oral clefts (cleft lip and palate), Nephrotic syndrome, Melanoma, Low birth weight/Small for Gestational Age, Immune suppression, Hepatocellular cancer (Liver cancer), Brain cancer ­adult
Chrysene Potential Effects - - -
Dibenzo (A,H) anthracene Potential Effects - - -
Dichloroethene Potential Effects - - -
Ethylbenzene Potential Effects - - -
Indeno pyrene Potential Effects - - -
Iron Potential Effects Bronchitis ­ chronic - Soft tissue sarcoma, Diabetes ­ Type II, Brain cancer ­adult, Alzheimer's
Lead Potential Effects Seizures, Reduced Fertility Male (infertility and subfertility), Peripheral neuropathy, Hypertension, Gout, Developmental Delay, Decreased I.Q../Mental retardation, Decreased Coordination/ Dysequilibrium, Coronary artery disease, peripheral vascular disease, atherosclerosis, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Chronic renal disease, Behavioral problems, Anemia ­ hemolytic, ADD/ADHD, hyperactivity, Abnormal sperm (morphology, motility, and sperm count) Reduced Fertility ­ Female (infertility and subfertility), Psychiatric disturbances, Pre­term delivery, Porphyria ­ toxic, Pancreatic cancer, Nephrotic syndrome, Low birth weight/Small for Gestational Age, Immune suppression, Hearing loss, Glomerulonephritis, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Delayed growth, Cardiomyopathy, Arrhythmias, Altered time to sexual maturation (accelerated or delayed puberty) Wilm's Tumor, Uterine cancer, Thyroid disorders ­Hypothyroidism, Stomach cancer, Reduced Fertility Male (infertility and subfertility), Osteoporosis, Neurosthenia (Organic affective syndrome), Lung cancer, Hepatocellular cancer (Liver cancer), Erectile dysfunction, Diabetes ­ Type II, Congenital malformation Cranio­ Facial, Colo­rectal cancer, Carcinoid, Breast cancer, Brain cancer ­adult, Bladder cancer, Alzheimer's, Altered time to sexual maturation (accelerated or delayed puberty), ALS (Lou Gehrig's disease), Abnormal sperm (morphology, motility, and sperm count)
Manganese Potential Effects Parkinson's disease/Movement disorders, Cholestasis Psychiatric disturbances, Pneumonitis hypersensitivity, Pneumonia, Peripheral neuropathy, Decreased Coordination/ Dysequilibrium, Bronchitis ­ acute, ADD/ADHD, hyperactivity Skeletal malformations, Reduced Fertility Male (infertility and subfertility), Peripheral neuropathy, Neurosthenia (Organic affective syndrome), Neural tube defects/CNS malformations, Metal fume fever, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Erectile dysfunction, Delayed growth, COPD ­chronic obstructive pulmonary disease, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Arrhythmias
Naphthalene Potential Effects Methemoglobinemia Cataracts, Anemia ­ hemolytic -
Perchloroethylene (PCE) Potential Effects - - -
Polychlorinated Byphenyls (PCBs) Potential Effects Thyroid disorders ­Hypothyroidism, Porphyria ­ toxic, Developmental Delay, Decreased I.Q../Mental retardation, Cirrhosis, Chloracne, Behavioral problems, ADD/ADHD, hyperactivity Peripheral neuropathy, Pancreatic cancer, Menstrual disorders, Lymphoma non ­Hodgkin's, Low birth weight/Small for Gestational Age, Immune suppression, Hepatocellular cancer (Liver cancer), Dyslipidemia, hypercholesterolemia, Delayed growth, Congenital malformation Cranio­ Facial, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Bronchitis ­ chronic, Acute hepatocellular injury (Hepatitis), Abnormal sperm (morphology, motility, and sperm count) Testicular cancer, Reduced Fertility ­ Female (infertility and subfertility), Parkinson's disease/Movement disorders, Hypoactivity, Hypertension, Hyperkeratosis/Hyperpigmentation, Hearing loss, Endometriosis, Diabetes ­ Type I, Breast cancer, Bone cancer/Ewings sarcoma, Altered time to sexual maturation (accelerated or delayed puberty), Altered sex ratio
Polynuclear Aromatic Hydrocarbons (PAHs) Potential Effects Scrotal cancer, Porphyria ­ toxic, Laryngeal cancer Skin cancer (non­melanoma), Renal (kidney) cancer, Prostate cancer, Photosensitivity, Pancreatic cancer, Nasopharyngeal/Sino­Nasal cancer, Lung cancer, Immune suppression, Esophageal cancer, Breast cancer, Bladder cancer Reduced Fertility Male (infertility and subfertility), Oral cancer, Melanoma, Early onset menopause, Coronary artery disease, peripheral vascular disease, atherosclerosis, Colo­rectal cancer, Bone cancer/Ewings sarcoma, Adult­-Onset Leukemias
Tetrachloroethene (PERC) Potential Effects - - -
Thallium Potential Effects Peripheral neuropathy Alopecia Psychiatric disturbances, Menstrual disorders
Toluene (BTEX compounds) Potential Effects Fetal solvent syndrome/ Fetal Ethanol Syndrome, Congenital malformation Cranio­ Facial Steatosis (fatty liver), Scleroderma, Reduced Fertility ­ Female (infertility and subfertility), Menstrual disorders, Low birth weight/Small for Gestational Age, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Developmental Delay, Delayed growth, Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Autoimmune antibodies, positive ANA, Arrhythmias, Acute tubular necrosis, Acute hepatocellular injury (Hepatitis) Stomach cancer, Peripheral neuropathy, Neurosthenia (Organic affective syndrome), Neural tube defects/CNS malformations, Multiple myeloma, Immune suppression, Genito­urinary malformations (includes cryptorchidism, hypospadias), Decreased Coordination/ Dysequilibrium, Colo­rectal cancer, Color vision disturbance, Cirrhosis, Brain cancer ­adult, Asthma ­irritant, Acute hepatocellular injury (Hepatitis), Abnormal sperm (morphology, motility, and sperm count)
Trichloroethylene (TCE) Potential Effects Acute hepatocellular injury (Hepatitis) Scleroderma, Renal (kidney) cancer, Psychiatric disturbances, Lymphoma non ­Hodgkin's, Hepatocellular cancer (Liver cancer), Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Decreased Coordination/ Dysequilibrium, Cirrhosis, Childhood Leukemias, Cardiac congenital malformations, Autoimmune antibodies, positive ANA, Arrhythmias Trigeminal neuropathy, Testicular cancer, Systemic Lupus Erythematosus, Raynaud's phenomenon, Prostate cancer, Peripheral neuropathy, Pancreatitis, Pancreatic cancer, Oral clefts (cleft lip and palate), Neural tube defects/CNS malformations, Nephrotic syndrome, Multiple myeloma, Lung cancer, Low birth weight/Small for Gestational Age, Immune suppression, Hodgkin's Disease (lymphoma), Genito­urinary malformations (includes cryptorchidism, hypospadias), Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span), Choanal atresia, Cervical cancer, Brain cancer ­adult, Adult­-Onset Leukemias, ADD/ADHD, hyperactivity, Acute tubular necrosis
Vanadium Potential Effects COPD ­chronic obstructive pulmonary disease, Bronchitis ­ chronic, Asthma ­ allergic Acute tubular necrosis Reduced Fertility ­ Female (infertility and subfertility), Pneumonia, Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth), Bronchitis ­ acute
Xylene Potential Effects - Scleroderma, Menstrual disorders, Arrhythmias Stomach cancer, Peripheral neuropathy, Delayed growth, Colo­rectal cancer, Brain cancer ­adult, Acute hepatocellular injury (Hepatitis)
Zinc Potential Effects Skin ulceration - Testicular cancer

If you lived or worked on Edwards Air Force Base and have experienced adverse health effects, you may be eligible for compensation.

*Effects are according to the Center for Disease Control and Prevention’s Agency for Toxic Substances & Disease Registry unless otherwise noted.