Middletown Air Depot

Location
Middletown, PA
Known Toxins
16
Years of Operation
1931-Present
Middletown Air Depot
Middletown Air Depot

Base Background

Middletown Air Depot was established in 1931 and is now the Harrisburg International Airport. The site focused on aircraft maintenance and material supply, particularly during World War II. Some of the base structures were demolished for airport construction.

Known Toxins

The following chart outlines the medical conditions associated with toxic exposure at this base, classified by the strength of evidence required (strong, good or limited).* Please keep in mind that it is not a complete list.

Toxin Potential Effects & Strength of Evidence Needed
Strong Good Limited
Arsenic Potential Effects & Strength of Evidence Needed
Peripheral neuropathy
Hyperkeratosis/Hyperpigmentation...
Diabetes ­ Type II
Coronary artery disease, peripheral vascular disease, atherosclerosis
MoreLess
Steatosis (fatty liver)
Skeletal malformations...
Renal (kidney) cancer
Raynaud's phenomenon
Pneumonitis hypersensitivity
Neural tube defects/CNS malformations
Nasal septal perforation
Myocardial ischemia
Low birth weight/Small for Gestational Age
Hypertension
Hepatoportal Sclerosis
Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth)
Congenital malformations ­ general
Cirrhosis
Cardiomyopathy
Bladder cancer
Arrhythmias
Anemia ­ hemolytic
Alopecia
Adult­-Onset Leukemias
MoreLess
Neurosthenia (Organic affective syndrome)
Myelodysplastic syndrome...
Metal fume fever
Immune suppression
Hepatocellular cancer (Liver cancer)
Genito­urinary malformations (includes cryptorchidism, hypospadias)
Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span)
Acute tubular necrosis
MoreLess
Barium Potential Effects & Strength of Evidence Needed -
MoreLess
-
MoreLess
Sarcoidosis
Arrhythmias
MoreLess
Benzene Potential Effects & Strength of Evidence Needed
Myelodysplastic syndrome
Multiple myeloma...
Aplastic anemia
MoreLess
Scleroderma
Renal (kidney) cancer...
Pre­term delivery
Menstrual disorders
Lymphoma non ­Hodgkin's
Autoimmune antibodies, positive ANA
Arrhythmias
MoreLess
Peripheral neuropathy
Neural tube defects/CNS malformations...
Nasopharyngeal/Sino­Nasal cancer
Lung cancer
Immune suppression
Hepatocellular cancer (Liver cancer)
Cardiac congenital malformations
Breast cancer
Brain cancer ­adult
Asthma ­irritant
MoreLess
Cadmium Potential Effects & Strength of Evidence Needed
Renal stones
Osteoporosis...
Itai­itai disease
Chronic renal disease
Acute tubular necrosis
MoreLess
Reduced Fertility Male (infertility and subfertility)
Prostate cancer...
Pneumonia
Nephrotic syndrome
COPD ­chronic obstructive pulmonary disease
Cardiomyopathy
Anemia ­ hemolytic
MoreLess
Testicular cancer
Soft tissue sarcoma...
Renal (kidney) cancer
Pulmonary fibrosis
Pulmonary edema
Peripheral neuropathy
Pancreatic cancer
Oral clefts (cleft lip and palate)
Neural tube defects/CNS malformations
Metal fume fever
Menstrual disorders
Immune suppression
Hypoactivity
Hypertension
Genito­urinary malformations (includes cryptorchidism, hypospadias)
Decreased I.Q../Mental retardation
Congenital malformation Cranio­ Facial
Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span)
Brain cancer ­adult
Autoimmune antibodies, positive ANA
Arrhythmias
ADD/ADHD, hyperactivity
Abnormal sperm (morphology, motility, and sperm count)
MoreLess
Carbon tetrachloride Potential Effects & Strength of Evidence Needed
Steatosis (fatty liver)
Cirrhosis...
Acute tubular necrosis
Acute hepatocellular injury (Hepatitis)
MoreLess
Scleroderma
Porphyria ­ toxic...
Lymphoma non ­Hodgkin's
Childhood Leukemias
Autoimmune antibodies, positive ANA
Arrhythmias
Aplastic anemia
Adult­-Onset Leukemias
MoreLess
Renal (kidney) cancer
Pancreatitis...
Pancreatic cancer
Oral clefts (cleft lip and palate)
Nephrotic syndrome
Melanoma
Low birth weight/Small for Gestational Age
Immune suppression
Hepatocellular cancer (Liver cancer)
Brain cancer ­adult
MoreLess
Chlorobenzene Potential Effects & Strength of Evidence Needed -
MoreLess
-
MoreLess
-
MoreLess
Chloroethene Potential Effects & Strength of Evidence Needed -
MoreLess
-
MoreLess
-
MoreLess
Chromium Potential Effects & Strength of Evidence Needed
Skin ulceration
Parkinson's disease/Movement disorders...
Nasopharyngeal/Sino­Nasal cancer
Nasal septal perforation
Nasal polyps
Cholestasis
Bronchitis ­ acute
Asthma ­ allergic
MoreLess
Stomach cancer
Pulmonary fibrosis...
Psychiatric disturbances
Pneumonitis hypersensitivity
Pneumonia
Photosensitivity
Peripheral neuropathy
Decreased Coordination/ Dysequilibrium
COPD ­chronic obstructive pulmonary disease
Chronic renal disease
Bronchitis ­ acute
Brain cancer ­adult
ADD/ADHD, hyperactivity
Acute tubular necrosis
MoreLess
Soft tissue sarcoma
Skeletal malformations...
Renal (kidney) cancer
Reduced Fertility Male (infertility and subfertility)
Prostate cancer
Peripheral neuropathy
Pancreatic cancer
Neurosthenia (Organic affective syndrome)
Neural tube defects/CNS malformations
Metal fume fever
Immune suppression
Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth)
Esophageal cancer
Erectile dysfunction
Delayed growth
COPD ­chronic obstructive pulmonary disease
Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span)
Bladder cancer
Autoimmune antibodies, positive ANA
Arrhythmias
Adult­-Onset Leukemias
Abnormal sperm (morphology, motility, and sperm count)
MoreLess
Heavy metals (misc.) Potential Effects & Strength of Evidence Needed
Pneumonitis hypersensitivity
MoreLess
-
MoreLess
Multiple myeloma
Chronic renal disease
MoreLess
Iron Potential Effects & Strength of Evidence Needed
Bronchitis ­ chronic
MoreLess
-
MoreLess
Soft tissue sarcoma
Diabetes ­ Type II...
Brain cancer ­adult
Alzheimer's
MoreLess
Lead Potential Effects & Strength of Evidence Needed
Seizures
Reduced Fertility Male (infertility and subfertility)...
Peripheral neuropathy
Hypertension
Gout
Developmental Delay
Decreased I.Q../Mental retardation
Decreased Coordination/ Dysequilibrium
Coronary artery disease, peripheral vascular disease, atherosclerosis
Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span)
Chronic renal disease
Behavioral problems
Anemia ­ hemolytic
ADD/ADHD, hyperactivity
Abnormal sperm (morphology, motility, and sperm count)
MoreLess
Reduced Fertility ­ Female (infertility and subfertility)
Psychiatric disturbances...
Pre­term delivery
Porphyria ­ toxic
Pancreatic cancer
Nephrotic syndrome
Low birth weight/Small for Gestational Age
Immune suppression
Hearing loss
Glomerulonephritis
Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth)
Delayed growth
Cardiomyopathy
Arrhythmias
Altered time to sexual maturation (accelerated or delayed puberty)
MoreLess
Wilm's Tumor
Uterine cancer...
Thyroid disorders ­Hypothyroidism
Stomach cancer
Reduced Fertility Male (infertility and subfertility)
Osteoporosis
Neurosthenia (Organic affective syndrome)
Lung cancer
Hepatocellular cancer (Liver cancer)
Erectile dysfunction
Diabetes ­ Type II
Congenital malformation Cranio­ Facial
Colo­rectal cancer
Carcinoid
Breast cancer
Brain cancer ­adult
Bladder cancer
Alzheimer's
Altered time to sexual maturation (accelerated or delayed puberty)
ALS (Lou Gehrig's disease)
Abnormal sperm (morphology, motility, and sperm count)
MoreLess
Nickel Potential Effects & Strength of Evidence Needed
Asthma ­ allergic
MoreLess
Stomach cancer
Pulmonary fibrosis...
Pulmonary edema
Nasal septal perforation
Laryngeal cancer
Immune suppression
MoreLess
Soft tissue sarcoma
Renal (kidney) cancer...
Prostate cancer
Myocardial ischemia
Myelodysplastic syndrome
Metal fume fever
Mesothelioma
Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth)
Arrhythmias
MoreLess
Trichloroethanes Potential Effects & Strength of Evidence Needed -
MoreLess
-
MoreLess
Hormonal changes (levels of circulating sex hormones ­ FSH/LH, Inhibin, and/or estrogens, progesterones, and androgens)
MoreLess
Trichloroethylene (TCE) Potential Effects & Strength of Evidence Needed
Acute hepatocellular injury (Hepatitis)
MoreLess
Scleroderma
Renal (kidney) cancer...
Psychiatric disturbances
Lymphoma non ­Hodgkin's
Hepatocellular cancer (Liver cancer)
Fetotoxicity (Miscarriage/spontaneous abortion; stillbirth)
Decreased Coordination/ Dysequilibrium
Cirrhosis
Childhood Leukemias
Cardiac congenital malformations
Autoimmune antibodies, positive ANA
Arrhythmias
MoreLess
Trigeminal neuropathy
Testicular cancer...
Systemic Lupus Erythematosus
Raynaud's phenomenon
Prostate cancer
Peripheral neuropathy
Pancreatitis
Pancreatic cancer
Oral clefts (cleft lip and palate)
Neural tube defects/CNS malformations
Nephrotic syndrome
Multiple myeloma
Lung cancer
Low birth weight/Small for Gestational Age
Immune suppression
Hodgkin's Disease (lymphoma)
Genito­urinary malformations (includes cryptorchidism, hypospadias)
Cognitive impairment (includes impaired learning, impaired memory, and decreased attention span)
Choanal atresia
Cervical cancer
Brain cancer ­adult
Adult­-Onset Leukemias
ADD/ADHD, hyperactivity
Acute tubular necrosis
MoreLess
Volatile organic compounds (VOCs) Potential Effects & Strength of Evidence Needed
Rhinitis ­ irritant
MoreLess
-
MoreLess
-
MoreLess
Zinc Potential Effects & Strength of Evidence Needed
Skin ulceration
MoreLess
-
MoreLess
Testicular cancer
MoreLess
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If you were stationed at Middletown Air Depot and later experienced adverse health effects, you may be eligible for compensation. Contact our Pennsylvania VA disability lawyers for a free evaluation of your case.

*Effects are according to the Center for Disease Control and Prevention’s Agency for Toxic Substances & Disease Registry unless otherwise noted.

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